David Tennant and Jessica Hynes are to star in a new comedy-drama about bringing up a girl with a severe learning disability.

There She Goes has been written by Shaun Pye, based on his own experiences. His daughter was born in 2006 with an extremely rare and, to date, undiagnosed chromosomal disorder.

Tennant and Hynes star as the parents of nine-year-old Rosie (Miley Locke) and her brother Ben (Edan Hayhurst), dealing with day-to-day such as trying to take their daughter to the park or trying to explain that every day isn’t her birthday.

A second timeline from the time of Rosie’s birth shows the impact having a severely disabled child had on the family.

The five-part series will air on BBC Four and is being made by Merman, the production company founded and run by Sharon Horgan and producer Clelia Mountford.

Pye is a writer on Have I Got News For You and co-created The Increasingly Poor Decisions of Todd Margaret with David Cross.

Hynes and Tennant have appeared in several shows and films  together over the years including Doctor Who (pictured), Nativity 2: Danger In The Manger and Stephen Mangan’s forthcoming Channel 4 therapy comedy, Hang Ups

Tennant also narrated both W1A and its predecessor Twenty Twelve, starring Hynes as annoying PR guru Siobhan Sharpe

Filming will begin on There She Goes next month.

All the news from today’s BBC press event:

• Horrible Histories team are making a new sitcom, Ghosts
•  Inside No 9 is to make a live one-off Halloween episode
• Series 2 of Motherland has been confirmed
• Pls Like is to return
• A new batch of female-led pilots had been commissioned for BBC Three
• David Tennant and Jessica Hynes are to star in a new comedy-drama about bringing up a girl with a severe learning disability.
• Daisy Haggard is to star as an ex-con in a new comedy she co-wrote with Laura Solon.
• A one-off special will mark the 60th birthday of Lenny Henry
• The Felix Dexter Bursary for aspiring BAME comedy writers is returning